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This mode of action reduced production of viral antigens (HBsAg and HBeAg) and impeded transcriptional elongation, distinguishing it from nucleoside analogs that target viral polymerase (Table 1, Row 21)
Kaikati, J., El Bcherawi, N., Khater, J.A., Dib, S.M., Kechichian, E
Carbapenemase-producing Klebsiella pneumoniae bloodstream infections: lowering mortality by antibiotic combination schemes and the role of carbapenems
Although the same concentration of CPP-CAND was applied to each cell type, caspase 3/7 activity was only observed in 44% of the senescent cells, whereas almost no activity was observed in dividing cells (Figure